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Lemmon 714 is a sedative and hypnotic medication. It was sold under the brand names Quaalude and Sopor among others, and sold as a combination drug under the brand name Mandrax which contained 300 mg methaqualone and 25mg diphenhydramine within the same tablet. The commercial production of methaqualone was halted due to widespread abuse and addictiveness. It is a member of the quinazolinone class.
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Methaqualone, sold under the brand name Quaalude in the US and Mandrax in the UK and South Africa, is a sedative and hypnotic medication. It is a member of the Quinazolinone class.
The sedative-hypnotic activity of methaqualone was first noted by researchers in the 1950s. In 1962, methaqualone was patented in the US by Wallace and Tiernan. Its use peaked in the early 1970s as a hypnotic, for the treatment of insomnia, and as a sedative and muscle relaxant.
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Methaqualone is a sedative that increases the activity of the GABA receptors in the brain and nervous system, similarly to benzodiazepines and barbiturates. When GABA activity is increased, blood pressure drops, and breathing and pulse rates slow, leading to a state of deep relaxation. These properties explain why methaqualone was originally mainly prescribed for insomnia.
Methaqualone became increasingly popular as a recreational drug and club drug in the late 1960s and 1970s, known variously as “ludes” or “sopers” (also “soaps”) in the U.S. and “mandrakes” and “mandies” in the UK, Australia, and New Zealand. The drug was often used by hippies and by people who went dancing at glam rock clubs in the 1970s and at discos. The drug was so popular in the disco scene of the 1970s that the drug, sold under the brand name Quaaludes, was nicknamed disco biscuits. Buy Quaaludes online.